Management of plaquenil maculopathy

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  1. koteyka User

    Management of plaquenil maculopathy


    Pattern of Retinopathy: Although the locus of toxic damage is parafoveal in many eyes, Asian patients often show an extramacular pattern of damage. Dose: We recommend a maximum daily HCQ use of 5.0 mg/kg real weight, which correlates better with risk than ideal weight.

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    Hydroxychloroquine HCQ is an anti-malarial medication that has in recent times been utilized as treatment for a variety of autoimmune diseases, such as rheumatoid arthritis and systemic lupus erythematosus, and other inflammatory and dermatologic conditions. Hydroxychloroquine sulfate HCQ, Plaquenil is an analogue of chloroquine CQ, an antimalarial agent, used for the treatment of systemic lupus erythematosus, rheumatoid arthritis and other autoimmune disorders. Its use has been associated with severe retinal toxicity, requiring a discontinuation of therapy. Find user ratings and reviews for Plaquenil oral on WebMD including side effects and drug interactions, medication effectiveness, ease of use and satisfaction

    Risk of Toxicity: The risk of toxicity is dependent on daily dose and duration of use. There are no similar demographic data for CQ, but dose comparisons in older literature suggest using 2.3 mg/kg real weight.

    Management of plaquenil maculopathy

    Hydroxychloroquine Plaquenil Toxicity and., Retinal toxicity associated with chronic exposure to hydroxychloroquine.

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  4. Toxic maculopathy associated with chloroquine use was first documented in the literature five decades ago.1 In the United States, Plaquenil––an analog to chloroquine––is used to treat a variety of conditions, including rheumatoid arthritis, lupus and several distinct inflammatory disorders.

    • New Plaquenil Guidelines.
    • Plaquenil oral Reviews and User Ratings Effectiveness..
    • Eye screening for patients taking hydroxychloroquine Plaquenil.

    Plaquenil-induced maculopathy is a form of retinal toxicity that is associated with long-term use of of the anti-inflammatory medication plaquenil. The drug-induced maculopathy is associated with the following risk factors Cumulative dose level of 1,000 grams of plaquenil. Patients with existing retinal or macular disease. If abnormalities are present only unilaterally, investigate other causes besides hydroxychloroquine toxicity see “Differential Diagnosis of Bull’s-Eye Maculopathy”. Mechanism of Toxicity. The mechanism of hydroxychloroquine retinal toxicity has yet to be fully elucidated. H ydroxychloroquine HCQ; Plaquenil, Sanofi, Bridgewater, NJ is an antimalarial agent that is also commonly used as a treatment for a variety of rheumatologic and dermatologic conditions, such as rheumatoid arthritis and systemic lupus erythematosus.

     
  5. nevidiDIMKA Moderator

    Suppression: 400 mg (310 mg base) orally on the same day every week Comments: -Suppressive therapy should begin 2 weeks prior to exposure; however, failing this, an initial dose of 800 mg (620 mg base) may be taken in 2 divided doses (6 hours apart). Rheumatoid Arthritis Treatment Options Johns Hopkins. Hydroxychloroquine Plaquenil Side Effects & Dosage for. Drug Safety in Pregnant & Nursing Women
     
  6. wassilly Moderator

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  7. [email protected] Moderator

    Plaquenil - when to take the 2 doses? - HealthBoards Hi, I saw a rheumy for the first time last week, and he prescribed plaquenil, 200 mg twice a day. Didn't diagnose with Lupus yet, but said I definitely have something autoimmune going on and the plaq will help with the fatigue. He warned that it could take 2-6 months, though, which is what I've read here too.

    I take Plaquenil 200MG TAB.tablet twice daily I.