Few adequate, well-controlled studies evaluating the potential for metabolic and/or pharmacologic interactions between botanicals and COUMADIN exist. Due to a lack of manufacturing standardization with botanical medicinal preparations, the amount of active ingredients may vary. Ocular testing for plaquenil Plaquenil help with fatigue One of the most serious side effects is a toxicity in the eye generally with chronic use. People taking 400 mg of hydroxychloroquine or less per day generally have a negligible risk of macular toxicity, whereas the risk begins to go up when a person takes the medication over 5 years or has a cumulative dose of more than 1000 grams. Summary Drug interactions are reported among people who take Warfarin sodium and Plaquenil together. This study is created by eHealthMe based on reports of 204 people who take Warfarin sodium and Plaquenil from Food and Drug Administration FDA, and is updated regularly. We would like to show you a description here but the site won’t allow us. Monitor the patient's response with additional INR determinations when initiating or discontinuing any botanicals. This could further confound the ability to assess potential interactions and effects on anticoagulation. Warfarin interaction with hydroxychloroquin Sulfasalazine oral and warfarin oral Drug Interactions - RxList, Warfarin sodium and Plaquenil drug interactions - eHealthMe Chloroquine diphosphate selleckchemEfectos de hydroxychloroquine en la vistaPlaquenil eye exam frequency Warning in Coumadin Package Insert Exercise caution when botanical herbal products are taken concomitantly with COUMADIN. Few adequate, well-controlled studies evaluating the potential for metabolic and/or pharmacologic interactions between botanicals and COUMADIN exist. Due to a lack of. Food and Supplement Interactions with Warfarin UC San Diego.. . Meloxicam Oral Route Before Using - Mayo Clinic. Drug Interaction Classification Systems Significance Rating A Criteria Management Rating B Criteria 0 Not listed 0 Not listed 1 Severity - Major The effects are potentially life-threatening or capable of causing permanent damage. Digoxin, cyclosporine, and certain beta blockers may cause drug interactions with hydroxychloroquine. This eMedTV segment explores what may happen if these drugs are taken with hydroxychloroquine and lists other drugs that may cause an interaction. Despite the availability of evidence of the interaction between acetaminophen and warfarin since the 1960s, data concerning the clinical significance of the interaction remains scarce. Recommendations regarding the management of patients taking both drugs are not strong because no studies examining outcomes, such as major bleeding, exist.