Is chloroquine injection safe in early pregnancy

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  1. Katryn XenForo Moderator

    Is chloroquine injection safe in early pregnancy

    This medicine is also sometimes given off-label to help the following conditions: Also, let your doctor know if you drink large amounts of alcohol before starting on this medicine. Your doctor will probably want to order frequent tests to check your body's response to chloroquine.

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    Aralen chloroquine is an antimalarial drug used for the treatment of malaria and extraintestinal amebiasis. Common side effects are reduced hearing, tinnitus, nausea, vomiting, and diarrhea. Dosage, drug interactions, and pregnancy and breastfeeding safety are provided. Dec 14, 2011 Symptomatic and asymptomatic malaria infections during the first trimester of pregnancy were associated with miscarriage; treatment appeared to be safe. Malaria during pregnancy has adverse effects, including maternal mortality, miscarriage, and low birthweight. Find patient medical information for Chloroquine Oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings.

    Let your healthcare provider know if your symptoms either don't improve or worsen while taking this medicine. Keep all appointments with your doctor and laboratory.

    Is chloroquine injection safe in early pregnancy

    Is It Safe to Get Vaccinations During Pregnancy? - WebMD, First-Trimester Malaria Treatment and Outcomes

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  5. A cohort of 169 births to women who were exposed throughout pregnancy to chloroquine 300 mg base once a week for chemosuppression of malaria was studied. The birth defects in this cohort were compared with those in a control group of 454 births to women who were not exposed to chloroquine, most of whom lived in non-malarious areas.

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    In early pregnancy, there are two hormones that tend to increase in the body following implantation -- progesterone and human chorionic gonadotropin hCG. Levels of both hormones tend to rise in women with viable pregnancies but fall in women with an impending miscarriage. The purpose of this study is to test prevention strategies for pregnancy-related malaria. Researchers will compare different malaria treatments and treatment schedules which include chloroquine therapy weekly doses versus being dosed twice during pregnancy for 3 days each time to the standard practice of preventive treatment intervals in pregnancy with the drug sulfadoxine-pyrimethamine. Since chloroquine is found to be less toxic and highly effective, it is favoured as the drug of choice in the chemotherapy of malaria eradication. Since there have been no reports of teratogenicity associated with chloroguine 1, its safe use during pregnancy has been recommended 2.

  6. Jonny Mad XenForo Moderator

    Chloroquine has long been used in the treatment or prevention of malaria from Plasmodium vivax, P. malariae, excluding the malaria parasite Plasmodium falciparum, for it started to develop widespread resistance to it. Inhibition of the Lysosomal Pathway of Protein Degradation in. Chloroquine - an overview ScienceDirect Topics A study of the mechanisms of chloroquine retinopathy. II.
  7. serzhb XenForo Moderator

    Taking Plaquenil for Rheumatoid Arthritis Plaquenil is generally well-tolerated, but side effects are possible. Common side effects linked to Plaquenil include nausea and diarrhea. Taking the medication with food eases nausea for most people taking the drug. Less common side effects include skin rashes, hair thinning, and weakness.