Antidote of chloroquine

Discussion in 'Canada Pharmaceuticals Online' started by sokolsem, 19-Mar-2020.

  1. ravip Guest

    Antidote of chloroquine


    Chloroquine has been extensively used in mass drug administrations, which may have contributed to the emergence and spread of resistance. It is recommended to check if chloroquine is still effective in the region prior to using it.

    Hydroxychloroquine thyroid Plaquenil treat lupus

    According to the researchers, chloroquine is a potential solution to bridge this gap. In part because chloroquine is cheap, relatively easy to produce in larger quantities and has been on the market for more than 85 years. The Chinese government has confirmed that chloroquine has a certain curative effect on the novel coronavirus disease. Aralen chloroquine is an antimalarial drug used for the treatment of malaria and extraintestinal amebiasis. Common side effects are reduced hearing, tinnitus, nausea, vomiting, and diarrhea. Dosage, drug interactions, and pregnancy and breastfeeding safety are provided. Chloroquine is a 4-aminoquinoline with antimalarial, anti-inflammatory, and potential chemosensitization and radiosensitization activities. Although the mechanism is not well understood, chloroquine is shown to inhibit the parasitic enzyme heme polymerase that converts the toxic heme into non-toxic hemazoin, thereby resulting in the accumulation of toxic heme within the parasite.

    The Centers for Disease Control and Prevention recommend against treatment of malaria with chloroquine alone due to more effective combinations. In areas where resistance is present, other antimalarials, such as mefloquine or atovaquone, may be used instead.

    Antidote of chloroquine

    Chloroquine poisoning • LITFL • Clinical Case Tox Conundrum, Aralen chloroquine Malaria Drug Side Effects & Dosage

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  7. No health authorities have certified Chloroquine as a cure for coronavirus. WHO, the foremost authority on the subject, according to the Director-General of the body, Tedros Adhanom Ghebreyesus, says while the organisation is currently conducting a number of drug trials, it does not expect a result before three weeks.

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    Abstract No therapy has been proved to be effective for patients with severe chloroquine poisoning, which is usually fatal. In a retrospective study of 51 cases, we found that ingestion of more tha. Chloroquine phosphate tablets should not be used in these conditions unless the benefit to the patient outweighs the potential risks. Usage in Pregnancy Usage of Chloroquine during pregnancy should be avoided except in the prophylaxis or treatment of malaria when the benefit outweighs the potential risk to the fetus. Warning for non-medical redditors Chloroquine is promising, but it's possible to OD on it and cause blindness among other things, especially if you have certain genetics. DIY not encouraged! Is anyone researching that, or are any of the regions fighting the outbreak trying that proactively?

     
  8. foureters User

    Chloroquine has long been used in the treatment or prevention of malaria from Plasmodium vivax, P. malariae, excluding the malaria parasite Plasmodium falciparum, for it started to develop widespread resistance to it. Chloroquine analogues in drug discovery new directions of. Chloroquine treatment of ARPE-19 cells leads to lysosome. Chloroquine & Hydroxychloroquine supporting chemo.
     
  9. personal-80 Moderator

    Applies to hydroxychloroquine: oral tablet Along with its needed effects, hydroxychloroquine (the active ingredient contained in Plaquenil) may cause some unwanted effects. Plaquenil and sun exposure Plaquenil Oral Uses, Side Effects, Interactions, Pictures. Lupus Photosensitivity and UV Light
     
  10. maverick79 Well-Known Member

    Post-exposure Chloroquine Prophylaxis COVID19 Because Chloroquine is cheap, abundant and low risk for short term dosage, it would be ideal as a single pill/weekly dose application to all contacts or people with cold like symptoms. Its about disease modification, not transmission prevention.

    Chloroquine & Hydroxychloroquine supporting chemo.