Because lupus is an autoimmune disease that affects the collagen tissue in the entire body, the collagen component of the mucosa of the mouth, including the gingival tissue and salivary glands also present the symptoms seen elsewhere in the body. A person with lupus demonstrates increased levels of xerosthemia or dry mouth leading to increased levels of caries, periodontitis and candidiasis. Hydroxychloroquine and epsom salt bath Ra treatment plaquenil Nifedipine and hydroxy chloroquine Gingival enlargement is an increase in the size of the gingiva. It is a common feature of gingival disease. Gingival enlargement can be caused by a number of factors, including inflammatory conditions and the side effects of certain medications. The treatment is based on the cause. A closely related term is epulis, denoting a localized tumor on the gingiva. Drug induced gingival hyperplasia can be caused by cyclosporine and calcium channel blockers. Angioedema of the lip can be a secondary reaction to ACE-inhibitors. ACE-inhibitors are used to treat hypertension. This reaction can also be a result of anti-seizure medications and immune-suppressants. Profile. Definition Gingival hyperplasia is defined as an enlargement of the gingiva that is noninflammatory, produced by factors other than local irritation, and the result of an increased number of cells. 1 Because gingival hyperplasia denotes a specific histologic diagnosis, clinicians must rule out other causes of gingival enlargement with biopsies of affected tissues. 2 A common example. What are called leukoplakic lesions (white scaly tissue detaching from the underlying tissue) can appear on the skin or mucosa of the cheek, palate, o r vermillion border of the lips. The gingival tissue may become red and appear to be desquamating. Hydroxychloroquine gingival hyperplasia Picture of Gingival Hyperplasia from Phenytoin, Oral Concerns in People With Lupus - Hospital for Special. Chloroquine pretreatment before transfection Here is more than you ever wanted to know, I am sure, about drug induced hyperplasia. In this case, "gingival hyperplasia". Just fancy words, gingival means gums, and hyperplasia means cells growing too fast, too many of them and they accumulate over time. Yesterday there was a post on ACOR about a patient with gingival overgrowth. CLL Topics Prescription Drug Induced Complications. Gingival Hyperplasia Clinician's Brief. Drug Therapy of Lupus - LUPUS UK. Provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Dec 05, 2019 Frequency not reported Gastrointestinal disorder, gingivitis, gingival hyperplasia. Dermatologic. Well-documented cases of rashes as leukocytoclastic vasculitis have been reported, but a definitive between these events and this drug have not been established. Lichenoid keratosis and hyperpigmentation occurred in skin exposed to the sun. Gingival hyperplasia, also known as gingival enlargement, is a swelling of the gum tissue gingiva. Hyperplasia specifically means an increase in the number of cells in the gum tissue. This increase in gingival cells has many different causes, but one of the most common is drug-induced gingival hyperplasia.