Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. Plaquenil and palindromic rheumatoid arthritis Side effects of too much plaquenil Plaquenil can cause loss of appetite and I agree that losing weight at this rate and suffering diarrhea is not healthy and might mean you become ill nourished and dehydrated. I suggest lowering the dose, going back to the original, until your tum has settled down then very gradually increasing it to give your body the maximum chance to adjust. At first I thought this was from anemia, but my bloodwork showed that I'm no longer very anemic. Then I discovered that plaquenil can have a side effect of hair loss. But I also know that lupus can too. I brought this up with my doctor and all he said was to take vitamin B. which is silly because I'm already on two different multivitamins. Find information about common, infrequent and rare side effects of Plaquenil Oral. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. Can taking plaquenil cause weight loss Rx Side Effects New Plaquenil Guidelines and More - American., Hair loss and Plaquenil? DailyStrength Plaquenil and humira interactionReducing inflammation without plaquenil Find patient medical information for Plaquenil Oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. Plaquenil Oral Uses, Side Effects, Interactions, Pictures.. Common and Rare Side Effects for Plaquenil Oral. Weight gain while on Plaquenil? lupus. Re want to know good stuff about plaquenil Sorry to be a party pooper here, but I have been on Plaquenil for 5 months and can't say I feel any difference at all. If anything I am sleeping all day but for just about 1 1/2 hours at a time. In rare cases, Plaquenil can cause cardiomyopathy, a chronic disease of the heart muscle. If you're taking Plaquenil for an autoimmune condition, your symptoms should begin to improve after a few. Hence, if the loss of appetite and weight loss started after you started on this drug, then yes, it could be due to Plaquenil. However, if you had loss of appetite and weight loss before your started this drug, then the drug can aggravate the process. In this case, the cause of loss f appetite and weight loss has to be found.