If you have access to a journal via a society or association membership, please browse to your society journal, select an article to view, and follow the instructions in this box. Contact us if you experience any difficulty logging in. Hydroxychloroquine hyperkalemia Hydroxychloroquine and neuropathy Does plaquenil help with sex drive Hyperpigmentation due to hydroxychloroquine for lupus? My relative has hyperpigmentation on her face from using hydroxychloroquine for her lupus. She's really self conscious about it and is looking for a solution. Hyperpigmentation occurs when a person develops darker patches on the skin, such as age spots or melasma. Learn about the causes, types, and treatments for hyperpigmentation here. Persistent cutaneous hyperpigmentation due to hydroxychloroquinone one year after therapy discontinuation L Katie Morrison MD 1,2, James J Nordlund MD 1, Michael P Heffernan MD 1 Dermatology Online Journal 15 12 15 1. Center for Clinical Studies, Houston, Texas 2. Wright State Dermatology, Dayton, Ohio Abstract In many cases, once the offending drug has been stopped, fading of the lesions occurs. Drug-induced skin pigmentation can become cosmetically disfiguring. Hyperpigmentation of the skin due to hydroxychloroquine Plaquenil Side Effects Common, Severe, Long Term -, Hyperpigmentation Treatment, types, and causes Chloroquine phosphate dosage reefPlaquenil and dental workPlaquenil and iron supplementsIs it ok to drink alcohol while taking plaquenilChloroquine: mechanism of drug action and resistance in plasmodium falciparum What Does Hydroxychlorqoune Hyperpigmentation Look like?How Common Is It?Why Does It occur?How Are The Abnormal Pigmented Areas Treated?Reference Skin Pigmentation with Hydroxychloroquine. Persistent cutaneous hyperpigmentation due to hydroxychloroquinone one.. Hydroxychloroquine-Induced Hyperpigmentation JCR Journal of Clinical.. Skin pigmentation related to antimalarials is described as yellow brown to slate gray or black pigmentation, which predominates on the anterior side of the shins but can also be seen in the face, forearms, mouth mucosa essentially hard palace and gingivae and nail beds. 16 This is consistent with our findings because all patients had skin. An elderly woman presented with 6 months history of skin coloured to erythematous papules in annular pattern over extremities, upper back and neck. The patient was diagnosed with granuloma annulare GA and started on hydroxychloroquine HCQ 300 mg daily. After 4 months of treatment, she developed bluish grey pigmentation within the plaques of GA with normal surrounding skin figure 1A,B. Hyperpigmentation of the skin due to hydroxychloroquine. Scandinavian J Rheumatol. 2008;372158. Lisi P, Assalve D, Hansel K. Phototoxic and photoallergic dermatitis caused by hydroxychloroquine.