It regulates the activity of the immune system, which may be overactive in some conditions. Hydroxychloroquine can modify the underlying disease process, rather than simply treating the symptoms. Malaria chloroquine Side effects of long term use of plaquenil Hydroxychloroquine HCQ, sold under the brand name Plaquenil among others, is a medication used for the prevention and treatment of certain types of malaria. Specifically it is used for chloroquine -sensitive malaria. Other uses include treatment of rheumatoid arthritis, lupus, and porphyria cutanea tarda. Hydroxychloroquine is an antimalarial drug which is relatively safe and well-tolerated agent for the treatment of rheumatoid arthritis. Chloroquine is another antimalarial agent that is also sometimes used. Plaquenil Hydroxychloroquine is used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as lupus & others. Hydroxychloroquine is often taken in combination with other drugs such as methotrexate. Over the long term hydroxychloroquine can reduce pain, swelling and joint stiffness. It may be as long as 12 weeks before you notice the benefits. Hydroxychloroquine plaquenil rheumatoid arthritis Hydroxychloroquine Plaquenil, Rheumatoid Arthritis Treatment Options Johns Hopkins. What is chloroquine aralen Hydroxychloroquine may be used with other arthritis medicines including other DMARDs such as methotrexate. steroid medicines such as prednisolone or cortisone injections into the joint. anti-inflammatory medicines NSAIDs such as naproxen Naprosyn and ibuprofen Brufen, Nurofen. simple pain. Hydroxychloroquine — Arthritis Australia. Plaquenil Hydroxychloroquine - Side Effects, Dosage.. What are the side effects of using hydroxychloroquine.. Originally, hydroxychloroquine was used to prevent and treat malaria and was considered very effective. Now it is generally used for rheumatoid arthritis, but it has also been shown to work well for juvenile arthritis, some lupus symptoms, and other types of autoimmune conditions. Plaquenil hydroxychloroquine is an effective medication for autoimmune conditions and malaria that comes with less side effects than other DMARDs. You will likely have to take additional medications to keep your rheumatoid arthritis in control. Some people may develop eye problems, so you’ll. Mar 27, 2012 Hydroxychloroquine Plaquenil is primarily used in combination with other drugs, including methotrexate and/or sulfasalazine for moderate to severe Rheumatoid Arthritis. It is only prescribed alone in patients with very mild symptoms, who are RF negative and have non-erosive disease.