This medicine is also sometimes given off-label to help the following conditions: Also, let your doctor know if you drink large amounts of alcohol before starting on this medicine. Your doctor will probably want to order frequent tests to check your body's response to chloroquine. Is hydroxychloroquine sulfate safe Chloroquine maculopathy emedicine Feb 05, 2018 Primaquine phosphate is recommended only for the radical cure of vivax malaria, the prevention of relapse in vivax malaria, or following the termination of chloroquine phosphate suppressive therapy in an area where vivax malaria is endemic. In an open-label crossover pharmacokinetic study, 16 healthy volunteers 4 males and 12 females aged 20 to 47 years were randomized into two groups of three sequential hospital admissions to receive a single oral dose of 30 mg base primaquine, 600 mg base chloroquine, and the two drugs together. Chloroquine Phosphate. Chloroquine is used to prevent or treat malaria caused by mosquito bites in countries where malaria is common. Malaria parasites can enter the body through these mosquito bites, and then live in body tissues such as red blood cells or the liver. Let your healthcare provider know if your symptoms either don't improve or worsen while taking this medicine. Keep all appointments with your doctor and laboratory. Primaquine chloroquine interaction Chloroquine and primaquine combining old drugs as a new., Pharmacokinetic interactions between primaquine and chloroquine. Plaquenil drug interaction cymbaltaWhat can you expect when you stop taking plaquenilChloroquine proguanil combination Choosing a Drug to Prevent Malaria. Considerations when choosing a drug for malaria prophylaxis Recommendations for drugs to prevent malaria differ by country of travel and can be found in Malaria Information by Country. Recommended drugs for each country are listed in alphabetical order and have comparable efficacy in that country. No. CDC - Malaria - Travelers - Choosing a Drug to Prevent Malaria. Chloroquine Oral Uses, Side Effects, Interactions, Pictures.. Primaquine - Side Effects, Dosage, Interactions - Drugs.. Primaquine phosphate is recommended only for the radical cure of vivax malaria, the prevention of relapse in vivax malaria, or following the termination of chloroquine phosphate suppressive therapy in an area where vivax malaria is endemic. Patients suffering from an attack of vivax Primaquine has been shown to be tolerated as well as or better than other standard regimens but may cause nausea and abdominal pain that can be decreased by taking the drug with food. Of importance, primaquine may cause oxidant-induced hemolytic anemia with methemoglobinemia, particularly in individuals with a deficiency of G6PD. Primaquine is an N-substituted diamine that is pentane-1,4-diamine substituted by a 6-methoxyquinolin-8-yl group at the N4 position. It is a drug used in the treatment of malaria and Pneumocystis pneumonia. It has a role as an antimalarial.