Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. Adverse reaction to plaquenil Plaquenil retinopathy risk factors Dr. Fung’s case involved a 48-year-old woman with lupus. Nine years after discontinuing medical therapy, the patient had new scotomas, difficulty reading and progression of bull’s-eye maculopathy. Plaquenil’s long half-life in the body can cause irreversible and progressive damage, Dr. Fung said. Signs and Symptoms. Patients who are in the earlier stages of the toxicity may not notice any symptoms although there are rare reports of paracentral scotoma which causes a problem in reading and diminished color vision. The patient may not be able to notice this change and will cause for the symptom to progress. In Sjögren’s, Plaquenil is used to treat many symptoms of Sjögren’s including fatigue, joint symptoms of arthritis and arthralgias joint pain, dry mouth and dry eyes. Similar to its use in systemic lupus erythematosus, many clinicians feel that it is useful in reducing general Sjögren’s “disease activity.” Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. What are symptoms of plaquenil eye problems Symptoms Plaquenil Maculopathy Retinal Diseases Eye., Plaquenil Toxicity - Symptoms, Treatment, Risk Factors. Chloroquine dosing in infants Is something wrong with your eyes? Find symptoms in the list below, then look to the right for associated eye problems and diseases. To learn more, click on the eye problem or disease for a pop-up window with a definition and links. Please note The information on this page is not intended as a. Eye Problems - Symptoms A to Z -. The Risk of Retinal Toxicity with Plaquenil. Common and Rare Side Effects for Plaquenil Oral. Some of the medications used to treat rheumatoid arthritis, such as prednisone a corticosteroid and Plaquenil hydroxychloroquine, can actually trigger eye problems. “Plaquenil, on rare. Eye damage due to Plaquenil is not common,” he says. “Rarely will anybody who has good vision and minimal symptoms develop loss of central vision or ability to read if annual screening is done and visual are symptoms reported as soon as they occur so the medication can be stopped if toxicity occurs. Common side effects Nausea and diarrhea This can often can be combatted by taking Plaquenil with food or milk. Dizziness Precautions with this side effect Do not drive, use machinery. Cramps. Headache. Dry skin. Loss of appetite.