She suffered from Sjogren syndrome and inflammatory arthritis and was currently treated with prednisone and methotrexate. She was previously treated with hydroxychloroquine (Plaquenil) 200mg bid (6.5mg/kg) for 10 years, which was stopped one year prior to presentation. Novo-chloroquine 250 mg effets secondaires Chloroquine phosphate dosage The American Academy of Ophthalmology released an updated set of screening recommendations for hydroxychloroquine Plaquenil and chloroquine to account for the many studies that have shown the effects of these medications on the retina 1. It succinctly makes the case for screening, and The differential diagnosis of bull’s eye maculopathy commonly includes drug induced- hydroxychloroquine or chloroquine retinopathy, Stargardt disease, cone dystrophy, and benign concentric macular dystrophy. MacTel should be added to the differential for bull’s eye maculopathy. Case report Chloroquine retinopathy, is a form of toxic retinopathy damage of the retina caused by the drugs chloroquine or hydroxychloroquine, which are sometimes used in the treatment of autoimmune disorders such as rheumatoid arthritis and systemic lupus erythematosus. This eye toxicity limits long-term use of the drugs. Review of systems: Blurred vision, halos, dry eye, dry mouth, gastroesophageal reflux, joint pain Pupils: Reactive to light in each eye from 5 mm in the dark to 2 mm in the light. Extraocular movements: Full, both eyes (OU) Confrontation visual fields: Full OU Intra-ocular pressure The optic nerves appeared healthy with a 0.3 cup-to-disc ratio. Past Ocular History: None Medical History: Sjogren syndrome and inflammatory arthritis, supraventricular tachycardia, anxiety, depression, peptic ulcer disease Medications: prednisone, methotrexate, amitriptyline, ranitidine, estradiol, tizanidine, diltiazem, Restasis Allergies: codeine, droperidol Family History: heart disease, arthritis, cancer Social History: occasional alcohol but no tobacco or intravenous drug use. Chloroquine maculopathy oct Hydroxychloroquine toxicity - EyeWiki, Macular Telangiectasia A cause of bull’s eye maculopathy Plaquenil tab 200mg costChloroquine blood plasma ratio Request PDF Optical Coherence Tomography Findings in Hydroxychloroquine and Chloroquine-Associated Maculopathy Background Vision loss and maculopathy associated with hydroxychloroquine and. Optical Coherence Tomography Findings in Hydroxychloroquine.. Chloroquine retinopathy - Wikipedia. Retinal Damage in Chloroquine Maculopathy. - PubMed Central PMC. Chloroquine phosphate tablets should not be used in these conditions unless the benefit to the patient outweighs the potential risks. Usage in Pregnancy Usage of Chloroquine during pregnancy should be avoided except in the prophylaxis or treatment of malaria when the benefit outweighs the potential risk to the fetus. Toxic maculopathy is epitomized by chloroquine retinopathy. The most characteristic field defect caused by macular involvement is a ringlike central scotoma with a small island of slightly lesser visual loss in its center, as shown in Fig. 12-27. 52 Thioridazine, a phenothiazine derivative, is another cause of pigmented maculopathy with. Some patients, toxicity may first present as pericentral retinopathy and thus requires screening outside the macula. We assume chloroquine retinopathy follows a similar course as hydroxychloroquine retinopathy and so these guidelines also apply to patients taking chloroquine therapy.