I don't know if it's just me but im feeling so much worse as though all my aches and pains have been increased & I feel like I've been run over by a tractor! I'm aware that it can take 3 months before I can feel the benefits but am I supposed to be feeling worse? Also, after the 3 months, when my body has adjusted to the tablets do you still get flares whilst on these tablets or does it stop that happening? It's probably not the hydroxy making you worse, it's probably just that your flare was on a tragectory to get worse anyway and the tablets just haven't kicked in yet. Getting out of bed with the kids in the morning is such a struggle and im getting awful stomach cramps and wind which i didnt have before. Wind is normal for some, you may find it dies down..not, see the doc. before my diagnosis I was tired,aneamic,stiff etc since the plaquenil I jus flare all the time. Color dx test in plaquenil toxicity Can plaquenil give you lymphoma 2d chemical structure of chloroquine Plaquenil for cfs Side Effects Nausea, stomach cramps, loss of appetite, diarrhea, dizziness, or headache may occur. If any of these effects persist or worsen, notify your doctor or pharmacist promptly. Remember. Yes, plaquenil is difficult to adjust first, but after the first year of treatment and side effects, the benefits outweigh the problems. So, stick with it. In my opinion, the plaque nil is keeping the immune system regulated and the pain and other symptoms described will reduce. Worsening of skin conditions If you have psoriasis, Plaquenil may make your condition worse. Talk to your doctor if you have this condition. Rare side effects Vision changes/loss of vision There is a chance that retinal damage will occur while taking hydroxychloroquine Plaquenil or chloroquine Aralen. If you are feeling that it's still too much to handle, you can go back to the doc and there may be another treatment to compliment what you're taking or maybe you need to increase the dose... Hope you start to feel the benefits soon, fingers crossed!! I have been on Plaquenil for years but a one off prescription of Quinoric made me very ill with nausea, stomach cramps and huge pain. If things don't improve goto hour doc and qote this site . got so ill they wanted me to go on chemo based drugs but I did not want that either. now they want me on a drug they use for people who gets epileptic fits to calm down the fibrio/flare pain. Some people's flares almost stop, some reduce in severity, some in frequency or both...depends on the person. it was so bad I just came off it for several months. I hate it and now cant come off it but cannot bear the fibrio type pain it has given me. Does plaquenil make an infection worse Side Effects of Plaquenil Hydroxychloroquine, Warnings, Uses, Plaquenil side effects - kidney problems? - Symptoms. Chloroquine proguanil malaria prophylaxis However, after discontinuation, he may initially experience a "relapse" where his Sjogrens symptoms are worse than before. This too should subside over time. It doesn't matter if he goes back on Plaquenil or hydroxychoroquine. Both should suppress his immune system and make him more vulnerable to infection. Do either hydroxychol/Plaquenil put you at risk for.. Plaquenil What You Need to Know - Kaleidoscope Fighting Lupus. Plaquenil Side Effects on Your Eyes and Vision. Check with your doctor right away if you or your child have a fever and sore throat, pale skin, unusual bruising or bleeding, or unusual tiredness or weakness. These may be symptoms of a blood problem. This medicine may decrease the amount of sperm men make and affect their ability to have children. One of the reasons that physicians feel comfortable in prescribing Plaquenil is its low risk to benefit ratio. This means that the side effects of Plaquenil are mild and infrequent compared with its potential benefits. As with any medication, allergic reactions including skin rashes and non-allergic reactions can occur. Hydroxychloroquine oral tablet is available as a brand-name drug and a generic drug. Brand name Plaquenil. Hydroxychloroquine comes only as a tablet you take by mouth. Hydroxychloroquine is used to treat malaria, lupus erythematosus, and rheumatoid arthritis.