Less than 50% of pregnancies in women with lupus have complications, but all lupus pregnancies are considered high-risk. Lupus can complicate pregnancy with an increased risk of miscarriage, premature delivery, and preeclampsia, as well as heart problems in the baby. Plaquenil and sjogrens syndrome Chloroquine base The future. Hydroxychloroquine was previously prescribed only for people whose lupus disease activity was mild in its course; if the lupus became active, steroids or immunosuppressants would be prescribed instead. Today, however, HCQ is recommended for most individuals with lupus, whether mild, moderate, or severe. It may prevent joint damage and reduce the risk of long-term disability. Hydroxychloroquine is in a class of medications that was first used to prevent and treat malaria. Today, it is used to treat rheumatoid arthritis, some symptoms of lupus, childhood arthritis or juvenile idiopathic arthritis. Clowse et al. found that women who stopped taking HCQ had increased lupus activity and increased lupus flares during pregnancy. High activity lupus was defined as a physician's estimate of activity PEA greater than 2 occurred in twice as many pregnancies in which HCQ treatment was stopped as in those in which HCQ was continued. “Preconception counseling allows women who have lupus to discuss their personal health with their doctor to assess risks based on how lupus has affected her thus far,” says Larry Matsumoto, MD, maternal fetal specialist at Atlanta Perinatal Consultants. If you have lupus and are considering having a baby, consider these tips to ensure a safe pregnancy and healthy baby. Hydroxychloroquine in lupus pregnancy PS Hydroxychloroquine in lupus pregnancy a meta-analysis., Hydroxychloroquine Plaquenil Plaquenil kidney transplantChloroquine concentration lysosomeCirrus oct plaquenil We conducted a randomized, controlled study to assess the need for hydroxychloroquine HCQ during lupus pregnancy and to assess safety. Twenty consecutive pregnant patients with similar. PDF Hydroxychloroquine HCQ in lupus pregnancy Double.. Systematic review of hydroxychloroquine use in pregnant.. Hydroxychloroquine prevents congenital heart block recurrence.. Hydroxychloroquine is also an antirheumatic medicine and is used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. Important information. Taking hydroxychloroquine long-term or at high doses may cause irreversible damage to the retina of your eye. Stop taking this medicine and call your doctor at once if you. Hydroxychloroquine Use in Lupus Patients during Pregnancy Is Associated with Longer Pregnancy Duration in Preterm Births Plaquenil hydroxychloroquine has a good safety record in lupus pregnancy, and is usually continued if needed to control maternal lupus. Management and Monitoring. Lupus pregnancy should be timed to coincide with a period of good disease control if at all possible.