The reaction can be phototoxic and/or photoallergic. Phototoxic reactions result from direct damage to tissue caused by light activation of the photosensitising agent, whilst photoallergic reactions are a cell-mediated immune response in which the is the light-activated photosensitising agent. Hydroxychloroquine in pregnancy and lactation Chloroquine diphosphate salt malaria Plaquenil is the brand name for the prescription drug hydroxychloroquine. It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as. I've read on medical sites that Hydroxychloroquine can react with the sun causing allergic reactions and I wonder if this is the cause of the rash on this occasion or whether it's just my normal photosensitivity. I've read some posts on the forum here about people reacting to Hydroxychloroquine but it seems to be very severe as you say twitchytoes. Plaquenil can improve photosensitivity. However imuran and other immunosuppressants, which I also take can worsen it. However imuran and other immunosuppressants, which I also take can worsen it. Thankfully for me that didn't happen and I still have a huge improvement on what I was like before where I would break out in a severe hive or blister like rash anywhere that was exposed. Although some oral photosensitising medications can cause photoallergic reactions, most cause phototoxic reactions. Photoallergic reactions occur less commonly than phototoxic reactions and are mostly caused by photosensitising topical agents. Plaquenil and photosensitivity Will you have Photosensitivity reaction with Plaquenil., Hydroxychloroquine and photosensitivity - LUPUS UK At risk lifetime dosage of hydroxychloroquineChloroquine side effects psoriasisChloroquin rezeptfreiHow often to take chloroquinePlaquenil adverse effects Hi everyone, I have Ra and was diagnosed with discoid Lupus last summer. My rheumy juggled my meds and added hydroxychloroquine 200mg. Approx a month after starting this I noticed I was getting more sun sensitive and had a nasty flare which has taken most of the winter to calm down. Hydroxychloroquine ~ sun sensitivity? Hi everyone.. Plaquenil and Sun Sensitivity - Reviews - Treato. Pictures of Photosensitivity, Symptoms, List of Drugs. Provocation with high dose UVA and UVB was similar with and without treatment with chloroquine or hydroxychloroquine. Our results have shown that photosensitivity during medication with chloroquine and hydroxychloroquine is uncommon and that there is no need to stop this treatment due to sun exposure. PMID 1439633 Indexed for MEDLINE MeSH terms Lupus patients have to stay out of the sun -the sensitivity and my rashes, lupus body flares increased drastically if I am in the sun. We are instructed to wear sunscreen underneath our clothing – you can use RIT -Sun Guard to wash your clothes and it gives it a 30 SPF for about 20 washes. Plaquenil hydroxychloroquine is an antimalarial medication used to treat or prevent malaria, a disease caused by parasites, which enter the body through the bite of a mosquito. Plaquenil is also used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus.