Areas of chloroquine resistant malaria

Discussion in 'Chloroquine' started by Gray_Lemon, 14-Mar-2020.

  1. aem New Member

    Areas of chloroquine resistant malaria


    Chloroquine has been extensively used in mass drug administrations, which may have contributed to the emergence and spread of resistance. It is recommended to check if chloroquine is still effective in the region prior to using it.

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    Since the first reports of chloroquine-resistant falciparum malaria in southeast Asia and South America almost half a century ago, drug-resistant malaria has posed a major problem in malaria control. By the late 1980s, resistance to sulfadoxine-pyrimethamine and to mefloquine was also prevalent on the Thai-Cambodian and Thai-Myanmar Thai-Burmese borders, rendering them established multidrug. Travel to areas with chloroquine-resistant malaria Chloroquine-resistant P. falciparum is found in all parts of the world except the Caribbean and countries west of the Panama Canal. Although chloroquine-resistant P. falciparum predominates in Africa, it is found in combination with chloroquine-sensitive P. vivax malaria in South America and Asia. Chloroquine-resistant strains of P. falciparum occur in all endemic areas except Central America west of the Panama Canal, Mexico, Hispaniola, and parts of China and the Middle East, and multidrug-resistant strains occur in Southeast Asia, South America, and sub-Saharan Africa.

    The Centers for Disease Control and Prevention recommend against treatment of malaria with chloroquine alone due to more effective combinations. In areas where resistance is present, other antimalarials, such as mefloquine or atovaquone, may be used instead.

    Areas of chloroquine resistant malaria

    Chloroquine Resistant Malaria –, Malaria - Chapter 4 - 2020 Yellow Book Travelers' Health.

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  4. P. falciparum or Species Not Identified – Acquired in Areas Without Chloroquine Resistance. For P. falciparum infections acquired in areas without chloroquine-resistant strains, which include Central America west of the Panama Canal, Haiti, and the Dominican Republic, patients can be treated with oral chloroquine. A chloroquine dose of 600 mg base = 1,000 mg salt should be given initially.

    • CDC - Malaria - Diagnosis & Treatment United States..
    • Malaria Travel & Health Guide, 2019 Online Book.
    • DRUG RESISTANT MALARIA CURRENT STATUS.

    QUESTION In India how to treat a child and adult suffering from malaria? ANSWER Chloroquine-resistant malaria has been observed in India and so the first line drug of choice should be an artemisinin-derivative in combination with another drug this group of medications are more generally known as "artemisinin-based combination therapies" or ACTs. For prophylaxis only in areas with chloroquine-sensitive malaria-Prophylaxis should start 1 to 2 weeks before travel to malarious areas; should continue weekly same day each week while in malarious areas and for 4 weeks after leaving such areas. Usual Pediatric Dose for Malaria. Infants and children Less than 60 kg The dramatic impact of chloroquine resistance on malaria mortality has long been underestimated because only a low proportion of malaria attacks are potentially lethal among persons continuously exposed since birth to high levels of transmission. There is an urgent need to change treatment policies in Africa.

     
  5. gadgetest Moderator

    500 mg chloroquine phosphate (300 mg base) orally on the same day each week Comments: -If possible, suppressive therapy should start 2 weeks prior to exposure; if unable to start 2 weeks before exposure, an initial loading dose of 1 g chloroquine phosphate (600 mg base) may be taken orally in 2 divided doses, 6 hours apart. CHLOROQUINE Drug BNF content published by NICE CHLOROQUINE PHOSPHATE, USP - Food and Drug Administration What is chloroquine? Trump, Elon Musk tout possible.
     
  6. ivannn User

    Symptoms of Hydroxychloroquine -- Teratogenic Agent. Symptoms of Hydroxychloroquine - Teratogenic Agent including 19 medical symptoms and signs of Hydroxychloroquine - Teratogenic Agent, alternative diagnoses, misdiagnosis, and correct diagnosis for Hydroxychloroquine - Teratogenic Agent signs or Hydroxychloroquine - Teratogenic Agent symptoms.

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