Swelling occurs most often on the face, lips, tongue, or throat, but it can happen anywhere in the body. The following may increase your risk or trigger symptoms: Your healthcare provider will examine you and ask about your symptoms. He may also ask about your family medical history, medicines you take, and foods you eat. Lupus and pregnancy plaquenil Plaquenil reviews for lupus What does plaquenil do to the immune system Hydroxychloroquine Plaquenil is considered a disease-modifying anti-rheumatic drug DMARD. It can decrease the pain and swelling of arthritis. It may prevent joint damage and reduce the risk of long-term disability. Hydroxychloroquine is in a class of medications that was first used to prevent and treat malaria. Angioedema can be caused by either mast cell degranulation or activation of the kallikrein-kinin cascade. In the former case, angioedema can be caused by allergic reactions caused by immunoglobulin E IgE-mediated hypersensitivity to foods or drugs that can also result in acute urticaria or a more generalized anaphylactic reaction. Plaquenil and Angioedema - from FDA reports Summary Angioedema is found among people who take Plaquenil, especially for people who are female, 60+ old, have been taking the drug for 1 month, also take medication Xolair, and have Cardiac failure. You may need additional testing if you developed anaphylaxis after you were exposed to a trigger and then exercised. You may need any of the following: You have the right to help plan your care. Tell your healthcare provider about any recent trauma, stress, or contact with allergens. Plaquenil for angioedema Angioedema - EMCrit Project, Angioedema - nih.gov Indication of chloroquineHydroxychloroquine blogIm chloroquine Plaquenil Side Effects by Likelihood and Severity INFREQUENT side effects. If experienced, these tend to have a Severe expression. A Type Of Allergic Reaction Called Angioedema; Common and Rare Side Effects for Plaquenil Oral. Will you have Angioedema with Plaquenil - eHealthMe. Plaquenil Uses, Dosage & Side Effects -. What is angioedema? Angioedema is sudden swelling caused by fluid that collects in deep layers of the skin. Swelling occurs most often on the face, lips, tongue, or throat, but it can happen anywhere in the body. What increases my risk for angioedema? The exact cause of angioedema is often unknown. The response to prednisone and rapidity of response suggests that the swelling is histamine dependent. I suspect that the angioedema is unrelated to the tingling of the tongue or the hydroxychloroquine. Since the disease being treated successfully is serious, I do not feel you must discontinue the hydroxychloroquine. Dosage for Plaquenil. The adult dose of Plaquenil to suppress malaria is 400 mg on the same day each week. The pediatric weekly suppressive dosage is 5 mg/kg of body weight. The adult dose of Plaquenil to treat an acute attack of malaria is an initial dose of 800 mg followed by 400 mg in six to eight hours and 400 mg for two more days.