He had a history of rheumatoid arthritis, and had been treated with hydroxychloroquine for the last 8 years. Echocardiography revealed a left ventricular ejection fraction of 25%, with diffuse hypokinesis. Lupus and plaquenil side effects Plaquenil pregnancy category australia Heart problems like heart failure and a certain abnormal heartbeat prolonged QT interval have happened with Plaquenil hydroxychloroquine. Sometimes, these heart problems have been deadly. Sometimes, these heart problems have been deadly. ATLANTA – Hydroxychloroquine Plaquenil 400 mg/day starting by pregnancy week 10 reduces recurrence of congenital heart block in infants born to women with anti-Ro antibodies, according to an open-label, prospective study presented at the annual meeting of the American College of Rheumatology. We present a case of twin sisters who both suffered from systemic lupus erythematosus SLE and HCQ-induced cardiomyopathy presenting with decompensated heart failure HF, suggesting that genetic predisposition might be a factor in HCQ-induced cardiomyopathy. The differential diagnosis for new onset non-ischemic cardiomyopathy in this patient included inflammatory cardiomyopathy, viral myocarditis, sarcoidosis, amyloidosis, hemochromatosis, Fabry's disease and HCQ toxicity. Coronary angiography demonstrated non-obstructive coronary disease. Treatment was initiated with guideline directed medical therapy, and patient clinically improved. Plaquenil and heart issues Plaquenil Side Effects on Your Eyes and Vision, Hydroxychloroquine prevents congenital heart block. Plaquenil price in u.s.aObgyn plaquenil lupus indianaChloroquine phosphate pricePlaquenil and pregnancy categoryChloroquine trpa1 itch Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except. What Conditions does Plaquenil Treat? - WebMD. Hydroxychloroquine-induced cardiomyopathy and heart failure in twins. HYDROXYCHLOROQUINE PLAQUENIL CARDIOTOXICITY AN UNCOMMON.. Long-Term Additive Cardiovascular Benefit of Plaquenil and Aspirin in Lupus By Jack Cush, MD 17 July 2017 Systemic lupus erythematosus SLE is associated with an increased risk of cardiovascular disease CVD. Hydroxychloroquine HCQ-induced cardiomyopathy is one of the rare but severe complications following prolonged HCQ use. However, the exact mechanism of HCQ cardiotoxicity remains unclear and it is difficult to identify risk factors. We present a case. Find information about common, infrequent and rare side effects of Plaquenil Oral.