Note that different people respond to different medications with varying levels of effectiveness. Thus, it may take time to find the most effective course of treatment. Plaquenil for chronic lyme Nabumetone lupus hydroxychloroquine Apr 04, 2007 I have RA and Plaquenil just got added to NSAID, MTX, and Prednisone. I am taking 400mg of Plaquenil, 20mg MTX, and 10mg Prednisone. I have only taken the Plaquenil for four days and every day I have a headache. It is not like a regular headache. It feels like someone has their hands on top of my head and pushing down on my head. Like I have pressure on the top of my head. I nver had this. One-third of the patients with active AS assigned to the high dose of oral prednisolone show a significantly greater response than those on placebo – a 50% improvement in the Bath Ankylosing Spondylitis Disease Activity Index BASDAI 50 versus just 8% -- after two weeks of treatment. I am looking for suggestions and experience on people who has ankylosing spondylitis and pass experience of a flare up. as for me, I am 37 years old, I been diagnose with AS for over 15 years. For the last few month, my ankylosing spondylitis has sudden flare-up. I was on Remicade for a few years now. NSAIDs are the most commonly used class of medication for the treatment of pain and stiffness associated with spondyloarthritis. SAA receives no government funding and relies on the generous donations from individuals to create and maintain the programs and services aimed at improving the futures of the 2.7 million Americans affected by spondylitis. Do prednisone and plaquenil work on ankylosing spondylitis Liesel Phillips - Is Plaquenil effective for ankylosing., Brief High-Dose Prednisone Improves Active Ankylosing Spondylitis Abatacept sulfasalazine hydroxychloroquine triple therapyIs plaquenil toxic Provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Prednisone User Reviews for Ankylosing Spondylitis at. Sudden ankylosing spondylitis Flare up. Effects of Ankylosing Spondylitis on the Body. Patient Frustration When biologics and other arthritis drugs don’t work for you I still remember my first visit with my rheumatologist when he told me I had psoriatic arthritis. It didn’t register. What in the world was psoriatic arthritis? I didn’t have psoriasis! As an RN I had taken care of patients. Ankylosing spondylitis should be treated early and aggressively. The goal of treatment is to keep the spine flexible and the joints moving before the disease causes bones to fuse together. Once the damage from Ankylosing Spondylitis is done, it cannot be reversed with medicine. Ankylosing Spondylitis must be stopped before it damages the joints. Nov 11, 2019 Prednisone is a potent corticosteroid drug used to treat inflammatory forms of arthritis as well as some types of cancer and autoimmune disease. It's available in tablet and liquid formulations and functions as an immunosuppressant, tempering inflammation by blunting the immune response.