It can decrease the pain and swelling of arthritis. It may prevent joint damage and reduce the risk of long-term disability. How does plaquenil work on the immune system Plaquenil and uveitis Hello all, I am currently new to this site and ran across the discussion about stopping Plaquenil. I have been taking Plaquenil for about 8-9 months and thought that it was not helping me because I still have a fair amount of joint pain, fatigue, muscle pain and so many other issues. Depending on how full your stomach it codine should take 20 min to a hour to work. It may take up to six months before the full benefits of Plaquenil are realized. Dosage The usual starting dose of Plaquenil is 200 mg twice a day or 400 mg once a day, administered orally, in people weighing 80 kg or more. Today, it is used to treat rheumatoid arthritis, some symptoms of lupus, childhood arthritis (or juvenile idiopathic arthritis) and other autoimmune diseases. Hydroxychloroquine is in a class of medications that was first used to prevent and treat malaria. How long does it take plaquenil to start working How long until Hydroxychloroquine takes effect - LUPUS UK, How long does it take for plaquenil to work - Answers How long plaquenil after positive anaHydroxychloroquine who makesDoes plaquenil help with sex driveSaltwater fish chloroquine compatible with meteoplex It may be 12 weeks or longer before you notice any benefit. Because it's a long-term treatment it's important to keep taking hydroxychloroquine unless you have severe side-effects even if it doesn't seem to be working at first even when your symptoms improve to help keep the disease under control. Hydroxychloroquine Side-effects, uses, time to work. Taking Plaquenil for Rheumatoid Arthritis. How long does plaquenil hydroxychloroquine take. - HealthTap. Indicates that you can expect to see some results after a month or two of taking hydroxychloroquine, but in order to get the full benefits you will need to take the medication for at least six months. That can help you realize how much benefit you’re going to actually get from the drug. The Plaquenil is supposed to kick in in 3 to 6 months. I think it was 8 months for me. One day I was congratulating myself for getting so many things done and I realised that the days had been getting better without my noticing. In the beginning I also was on a low dose of prednisone, which helped until plaquenil kicked in. How long does Plaquenil take to work? Plaquenil works very slowly. In 1 to 3 months you should start to feel better. You may continue to get better for up to 1 year. Most people who take Plaquenil also take other medicines for pain and stiffness. How does Plaquenil work? Plaquenil changes the way your immune system works.