In order to minimize the risks of infection and other potential complications with podiatric surgery in this patient population, this author reviews the literature and offers insights on whether medications for RA should be withdrawn, continued or modified during the perioperative period. Increasingly, the treatment of rheumatoid arthritis includes the utilization of immunosuppressive therapeutic agents. Plaquenil and low libido Benlysta and plaquenil Is plaquenil a steroid an immunosuppressant Plaquenil is prescribed as a disease-modifier, in other words, to decrease pain, decrease swelling, and prevent joint damage and disability. It is not known how Plaquenil works but researchers believe that Plaquenil interferes with communication between cells within the immune system. Ultimately, it is thought to block proinflammatory. The toxicity profile of hydroxychloroquine contributes little risk in stopping or continuing use during surgery since individuals are able to recover quickly with this medication after outpatient operations 20,21. It appears to be safe treatment for RA in the presence of elective surgery with renal function monitoring 17. Three hundred and eighty-eight patients undergoing elective orthopedic surgeries were randomized to either continue or to stop MTX therapy for 2 weeks before surgery and resume 2 weeks postoperatively. Louie and Ward demonstrated that in the state of California, rates of joint surgery for the treatment of RA declined in the 1990s and have continually diminished since that time.1 The authors concluded that the favorable long-term outcomes for the treatment of rheumatoid arthritis with newer agents have resulted in a decreased need for bone and joint surgery in patients afflicted with this disease. The effectiveness of disease modifying agents in reversing the progression of rheumatoid arthritis (RA) is illustrated by the reduced frequency with which patients with RA undergo surgery for bone and joint deformities. Stopping plaquenil for surgery Stopping Plaquenil before surgery Lupus Forums at The Lupus., The Safety of Elective Surgery with Concurrent Use of. Comparable drug to plaquenilChloroquine and proguanil tabletsRcophth hydroxychloroquine The Arthritis Foundation is focused on finding a cure and championing the fight against arthritis with life-changing information, advocacy, science and community. We can only achieve these goals with your help. Strong, outspoken and engaged volunteers will help us conquer arthritis. Get Involved - Arthritis Foundation Symptoms Treatments. Perioperative Management of Medications Used in the.. How Do Ophthalmologists Look for Plaquenil Damage.. It is ok and recommended to stop plavix for a week for the surgery and continue with other medications to decrease the risk of bleeding during surgery. Stopping the plavix for a few days does not increase the risk of a cardiac event. Hope this information is helpful. Taking Plaquenil long-term or at high doses may cause irreversible damage to the retina of your eye. Stop taking Plaquenil and call your doctor at once if you have trouble focusing, if you see light streaks or flashes in your vision, or if you notice any swelling or color changes in your eyes. Plaquenil is a 6-weeker as far as the benefits are concerned, but it would be more dangerous to stop if you spend a lot of time outside and if this were the summer. If you're gonna experiment, I went off it cold turkey as it didn't hurt to do it that way, but you better get back on before the summer or you could experience a flare-up.