Malaria is common in areas such as Africa, South America, and Southern Asia. This medicine is not effective against all strains of malaria. Chloroquine therapeutic class Plaquenil side effects skin rash Nov 18, 2013 Bad Side Effects of Plaquenil. I have been recently diagnosed with Lupus about 4 months ago and have started plaquenil with the hope it would relieve my symptoms no energy, achy body and severe hair loss. It seems as though it has helped the first two symptoms, but I have horrible constipation. Always tell the optician that you are on hydroxychloroquine. My rheumatologist says that it is a safe drug and has lots of benefits. Adverse effects on the eyes is very rare if you are on a safe dose. A safe dose depends on your weight. Aug 14, 2017 Plaquenil is the brand name of hydroxychloroquine, a drug used to prevent or treat malaria. Plaquenil can cause serious side effects when used in high doses for chronic diseases such as RA over the long term. Taking hydroxychloroquine long-term or at high doses may cause irreversible damage to the retina of your eye. Hydroxychloroquine is also an antirheumatic medicine and is used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. Hydroxychloroquine bad side effects Common and Rare Side Effects for Plaquenil Oral, How good is Hydroxychloroquine, and any side. - HealthUnlocked What's the difference between prime mcqueen and chloroquineCan i take zyrtec with plaquenilPlaquenil dosing for ra Hydroxychloroquine may cause some people to be agitated, irritable, or display other abnormal behaviors. It may also cause some people to have suicidal thoughts and tendencies, or to become more depressed. If you or your caregiver notice any of these side effects, tell your doctor right away. This medicine may cause hypoglycemia low blood sugar. Hydroxychloroquine Oral Route Precautions - Mayo Clinic. Long-Term Side Effects of Plaquenil for Rheumatoid Arthritis.. Plaquenil Oral Uses, Side Effects, Interactions, Pictures.. A very bad and sometimes deadly reaction has happened with hydroxychloroquine. Most of the time, this reaction has signs like fever, rash, or swollen glands with problems in body organs like the liver, kidney, blood, heart, muscles and joints, or lungs. Talk with the doctor. Keep away from children. Hydroxychloroquine received an overall rating of 7 out of 10 stars from 368 reviews. See what others have said about Hydroxychloroquine, including the effectiveness, ease of use and side effects. Nov 09, 2018 Common side effects may include headache, dizziness, ringing in your ears; nausea, vomiting, stomach pain; loss of appetite, weight loss; mood changes, feeling nervous or irritable; skin rash or itching; or. hair loss.