Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. Chloroquine transfection calcium phosphate Does hydroxychloroquine upset your stomach Plaquenil eye Trental and plaquenil together To the Editor We read the editorial by Sandhu, et al 1 about antimalarial-induced cardiomyopathy in systemic lupus erythematosus2, and we want to point out some inaccuracies in the brief review of the history of antimalarials that they presented. They state Address correspondence to L. Caminal-Montero, Autoimmune Diseases Unit, Internal Medicine, Hospital Universitario Central de Asturias. How does Plaquenil help me battle lupus? Antimalarials are able to help modulate the immune system. And, they have the additional benefit of not making your body more susceptible to infection a noted side effect of many other lupus medications. Hydroxychloroquine HCQ, sold under the brand name Plaquenil among others, is a medication used for the prevention and treatment of certain types of malaria. Specifically it is used for chloroquine-sensitive malaria. Other uses include treatment of rheumatoid arthritis, lupus, and porphyria cutanea tarda. It is taken by mouth. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. Antimalarials hydroxychloroquine Antimalarial Therapy in Patients Who Are Hydroxychloroquine., Plaquenil Hydroxychloroquine for Lupus - LupusCorner Chloroquine nail changes Three anti-malarial drugs are prescribed for lupus symptoms. Hydroxychloroquine Plaquenil is the most commonly prescribed because it is generally believed to cause fewer side effects; chloroquine Aralen has a reputation for more serious side effects, but it may be prescribed in situations where hydroxychloroquine cannot be used. Treating Lupus with Anti-Malarial Drugs Johns Hopkins Lupus Center. Hydroxychloroquine - Wikipedia. Plaquenil Side Effects Common, Severe, Long Term -. The antimalarials most often prescribed to people with lupus are Hydroxychloroquine Plaquenil® Chloroquine Aralen® Quinacrine Atabrine® 2-3; Hydroxychloroquine is prescribed the most often because it is thought to have the fewest side effects. Chloroquine and quinacrine are prescribed when hydroxychloroquine cannot be used. Antimalarials are used extensively in both RA and SLE. The major side effect is retinal toxicity, which requires ophthalmologic monitoring every 6–12 months. The favored antimalarial is hydroxychloroquine FDA Category C, which appears to have a lower incidence of retinal toxicity. Hydroxychloroquine Plaquenil™ What is hydroxychloroquine? Hydroxychloroquine also known as hydroxychloroquine sulfate is an arthritis medicine. that also can be used to prevent malaria. It is available in the United States by prescription only. It is sold under the brand name Plaquenil and it is also sold as a generic medicine. It is.