Im chloroquine

Discussion in 'Hydroxychloroquine' started by Violet, 24-Feb-2020.

  1. crate XenForo Moderator

    Im chloroquine


    -Suppressive therapy should continue for 8 weeks after leaving the endemic area. Approved indication: For the suppressive treatment of malaria due to Plasmodium vivax, P malariae, P ovale, and susceptible strains of P falciparum CDC Recommendations: 300 mg base (500 mg salt) orally once a week Comments: -For prophylaxis only in areas with chloroquine-sensitive malaria -Prophylaxis should start 1 to 2 weeks before travel to malarious areas; should continue weekly (same day each week) while in malarious areas and for 4 weeks after leaving such areas.

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    Chloroquine is a diprotic weak base and, at physiological pH ∼7.4, can be found in its un-protonated CQ, mono-protonated CQ + and di-protonated CQ ++ forms. The uncharged chloroquine is the only membrane permeable form of the molecule and it freely diffuses into the erythrocyte up to the DV. Chloroquine belongs to a group of medicines known as antimalarials. It works by preventing or treating malaria, a red blood cell infection transmitted by the bite of a mosquito. However, chloroquine is not used to treat severe or complicated malaria and to prevent malaria in areas or regions where chloroquine is known not to work resistance. Use of Chloroquine phosphate tablets in patients with psoriasis may precipitate a severe attack of psoriasis. When used in patients with porphyria the condition may be exacerbated. Chloroquine phosphate tablets should not be used in these conditions unless the benefit to the patient outweighs the potential risks. Usage in Pregnancy

    Approved indication: For acute attacks of malaria due to P vivax, P malariae, P ovale, and susceptible strains of P falciparum CDC Recommendations: Chloroquine-sensitive uncomplicated malaria (Plasmodium species or species not identified): 600 mg base (1 g salt) orally at once, followed by 300 mg base (500 mg salt) orally at 6, 24, and 48 hours Total dose: 1.5 g base (2.5 g salt) Comments: -For the treatment of uncomplicated malaria due to chloroquine-sensitive P vivax or P ovale, concomitant treatment with primaquine phosphate is recommended. 60 kg or more: 1 g chloroquine phosphate (600 mg base) orally as an initial dose, followed by 500 mg chloroquine phosphate (300 mg base) orally after 6 to 8 hours, then 500 mg chloroquine phosphate (300 mg base) orally once a day on the next 2 consecutive days Total dose: 2.5 g chloroquine phosphate (1.5 g base) in 3 days Less than 60 kg: First dose: 16.7 mg chloroquine phosphate/kg (10 mg base/kg) orally Second dose (6 hours after first dose): 8.3 mg chloroquine phosphate/kg (5 mg base/kg) orally Third dose (24 hours after first dose): 8.3 mg chloroquine phosphate/kg (5 mg base/kg) orally Fourth dose (36 hours after first dose): 8.3 mg chloroquine phosphate/kg (5 mg base/kg) orally Total dose: 41.7 mg chloroquine phosphate/kg (25 mg base/kg) in 3 days Comments: -Concomitant therapy with an 8-aminoquinoline compound is necessary for radical cure of malaria due to P vivax and P malariae.

    Im chloroquine

    Clinical Pharmacokinetics and Metabolism of Chloroquine SpringerLink, Chloroquine Oral, Intramuscular Advanced. -

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  6. Chloroquine is a medication used to prevent and to treat malaria in areas where malaria is known to be sensitive to its effects. Certain types of malaria, resistant strains, and complicated cases typically require different or additional medication. It is also occasionally used for amebiasis that is occurring outside the intestines, rheumatoid arthritis, and lupus erythematosus. It is taken by mouth. Common side effects include muscle problems, loss of appetite, diarrhea, and skin rash. Serious

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    Although widely considered dangerous, parenteral chloroquine is extensively used. We studied the acute disposition and toxicity of intravenous iv, intramuscular im, subcutaneous sc, and oral chloroquine in 60 adult Zambian patients hospitalized with falciparum malaria. Chloroquine is rapidly and almost completely absorbed from the gastrointestinal tract, and only a small proportion of the administered dose is found in the stools. Approximately 55% of the drug in the plasma is bound to nondiffusible plasma constituents. Excretion of chloroquine is quite slow, but is increased by acidification of the urine. Chloroquine-Sensitive Zones Chloroquine is the drug of choice for travel to areas where chloroquine resistance has not been described. Chloroquine is active against the erythrocytic forms Fig. 6.3 of sensitive strains of all species of malaria, and it is also gametocidal against P. vivax, P. malariae, and P. ovale.

     
  7. porh Moderator

    Applies to hydroxychloroquine: oral tablet Along with its needed effects, hydroxychloroquine may cause some unwanted effects. Plaquenil Hydroxychloroquine - Side Effects, Dosage, Interactions - Drugs Long-Term Side Effects of Plaquenil for Rheumatoid Arthritis. Plaquenil Withdrawal – Life As An Anomaly
     
  8. Fenrisar Moderator

    Plaquenil is the brand name for the prescription drug hydroxychloroquine. Side Effects of Plaquenil Hydroxychloroquine, Warnings, Uses Long-Term Side Effects of Plaquenil for Rheumatoid. Stomach problems with Plaquenil • Johns Hopkins Arthritis.
     
  9. Yad' User

    Etodolac Uses, Dosage, Side Effects - Etodolac is a nonsteroidal anti-inflammatory drug NSAID. It works by reducing hormones that cause inflammation and pain in the body. Etodolac is used to treat mild to moderate pain, osteoarthritis, or rheumatoid arthritis.

    Hydroxychloroquine User Reviews for Sjogren's Syndrome at
     
  10. decypher Moderator

    Plaquenil Hydroxychloroquine Uses, Dosage, Side Effects. Feb 19, 2020 Plaquenil Hydroxychloroquine may treat, side effects, dosage, drug interactions, warnings, patient labeling, reviews, and related medications including drug comparison and health resources. Drugs A-Z Pill Identifier Supplements Symptom Checker Diseases Dictionary Media

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