Chloroquine has been extensively used in mass drug administrations, which may have contributed to the emergence and spread of resistance. It is recommended to check if chloroquine is still effective in the region prior to using it. Aralen hydrochloride Chloroquine phosphate chemical structure Sep 15, 2001 These studies suggest chloroquine resistance arose in ⩾4 distinct geographic foci and substantiate an important role of immunity in the outcomes of resistant infections after chloroquine treatment. P. vivax which also causes human malaria, appears to differ from P. falciparum in its mechanism of chloroquine resistance. Investigation of the. Background. Afghanistan's national guidelines recommend chloroquine for the treatment of Plasmodium vivax infection, the parasite responsible for the majority of its malaria burden. Chloroquine resistance in P. vivax is emerging in Asia. Therapeutic responses across Afghanistan have not been evaluated in detail. What is P. vivax radical cure? Radical cure requires the administration of a combination therapy blood stage treatment in combination with liver stage treatment to clear all parasites. Blood stage treatment Chloroquine, or in areas where chloroquine resistance is prevalent, artemisinin-based combination therapy ACT to clear blood stages. The Centers for Disease Control and Prevention recommend against treatment of malaria with chloroquine alone due to more effective combinations. In areas where resistance is present, other antimalarials, such as mefloquine or atovaquone, may be used instead. Chloroquine treatment for vivax malaria Efficacy of chloroquine for the treatment of Plasmodium vivax., Dihydroartemisinin-piperaquine versus chloroquine to treat. Hydroxychloroquine sulphate tablets side effects Tafenoquine as a single-dose treatment coadministered with chloroquine effectively prevents P vivax relapse, and is a potential candidate for first-choice treatment of uncomplicated P vivax malaria, assuming that safety and efficacy at least equivalent to primaquine can be shown. Tafenoquine plus chloroquine for the treatment and relapse.. Radical cure PVIVAX - Malaria. Chloroquine - FDA prescribing information, side effects and uses. Treatment of uncomplicated malaria due to susceptible strains of P. falciparum, P.malariae, P. ovale, and P.vivax. Prophylaxis of malaria in geographic areas where resistance to Chloroquine is not present. Treatment of extraintestinal amebiasis. Chloroquine phosphate tablets do not prevent relapses in patients with vivax or ovale malaria. These gains, however, are threatened with the emergency of antimalarial drugs resistant strains of plasmodium parasites. This study aimed to determine therapeutic efficacy of chloroquine for treatment of Plasmodium vivax malaria cases in Guragae zone, southern central Ethiopia. Malaria. Chloroquine has long been used in the treatment or prevention of malaria from Plasmodium vivax, P. ovale, and P. malariae, excluding the malaria parasite Plasmodium falciparum, for it started to develop widespread resistance to it.