Since I have not taken it my chest feels so much better which is odd because chest pain is not listed as a side effect. Also I noticed that the Plaquenil I think was making me feel different but not in a good way. Retinal half life of plaquenil Plaquenil moa Quitting substance use suddenly and abruptly, or "cold turkey," carries very significant risks if the drug you are discontinuing is alcohol, a benzodiazepine or an opiate. It is also not advisable if you have been using any drug in large amounts and/or for a long time, because what you have been using may contain one of the high-risk drugs. If I skip plaquenil hydroxychloroquine for a few days then, and the vertigo stops would that be a sign it was from the med and not vestibular neuritis-? If plaquinil is the cause of muscle twitching/weakness if dr takes me off of it will muscle twitching stop? Why does plaquenil hydroxychloroquine cause thisis it serious Can you stop Plaquenil cold turkey" answer - YES. My rheumy told me to take time out on it for a month once. I really don't know why because he only told me to do it the once and I've been on it for six years now He said to give the system a rest for a moth and siad in his experience the disease seemed to be less active in January - so to do. Did you take yourself off Plaquenil, or did your doctor tell you to go off it? Plus I will be honest the whole eye site thing even though rare has always freaked me out. I went off of it to see if I can manage not being on it as my lupus isnt as severe as other cases but already I am feeling very fatigued and my legs feel heavy if that makes sense. I can discuss alternatives with my DR at my next appt but my DR feels as though the plaq is the best bet for my level of illness. If so are you just dealing with Lupus symptoms or did you take another med? I'm on Plaquenil, and after the first week's GI upset, I have had no problems with it. Does stopping hydroxychloroquine cold turkey What is the correct way to discontinue use of plaquenil?, What happens if I stop taking plaquenil hydroxychloroquine suddenly. Chloroquine macrophagesChloroquine dosage forms Hello all, I am currently new to this site and ran across the discussion about stopping Plaquenil. I have been taking Plaquenil for about 8-9 months and thought that it was not helping me because I still have a fair amount of joint pain, fatigue, muscle pain and so many other issues. Stopping plaquenil. DailyStrength. Can you quit plaquenil cold turkey, or have to wean. Plaquenil Withdrawal – Life As An Anomaly. But making the decision to become sober is a step worth taking. “Quitting can be done safely and is safer than continuing to drink heavily,” Dr. Richard Saitz, chair of the Department of. It may be that the original cold turkey was a combination of cold "straightforward, matter-of-fact" and the earlier talk turkey, which dates back to the early 1800s and refers to speaking plainly. Regardless of its ultimate origins, the phrase manages to vividly capture the initial dread and discomfort that comes from immediately quitting. I have read about people stopping P & flaring up. Those who stopped it abruptly had real problems similar to what you are experiencing. If you really need to get off it, I would taper down slowly, very slowly. There is a similar posting on Healthunlocked, "Why oh why did u stop taking plaquenil." You may want to check it out.