While these reviews might be helpful, they are not a substitute for the expertise, skill, knowledge and judgement of healthcare practitioners. "I started the hydroxychloroquine medication a week ago and within the first day or two noticed a big difference in my pain and fatigue with major improvement SLE. Plaquenil make toungue Hydroxychloroquine does Baseline labs required before starting plaquenil I just want to do something to help. Does icing the painful joints help? Heat? I just feel so helpless. The dr doesn't want to increase the pain meds and until the Plaquenil starts to do its thing which I understand can take a while I feel like we're stuck and she has no choice but to suffer through it. Is extreme fatigue a side effect of Plaquenil. Its suppose to help with fatigue and joint pain, and has slight blood thinning properties. May be worth looking at. Dec 05, 2017 I started on the Plaquenil a little over a week ago. Not much in the way of side effects. Some minor stomach stuff but that could be normal and not related to the Plaquenil. I started at 200mg and increased to 400mg after a week. Andie213, my fatigue has been frustrating for me as well. While there is good clinical evidence demonstrating the drug’s efficacy in rheumatoid arthritis and lupus, there are very few studies looking at hydroxychloroquine as a treatment for Sjögren’s. Plaquenil (hydroxychloroquine) is a medication that has been used for many years to help musculoskeletal symptoms and fatigue in patients with autoimmune conditions such as rheumatoid arthritis, lupus and Sjögren’s. Plaquenil help with fatigue Will you have Fatigue with Plaquenil - eHealthMe, Is extreme fatigue a side effect of Plaquenil - NRAS How to pronounce hydroxychloroquineChloroquine phosphate vs cupramineWww plaquenilMechanism of resistance to chloroquineChloroquine primaquine babesxia Hydroxychloroquine Plaquenil is used to treat malaria, lupus, and rheumatoid arthritis. Learn about side effects, warnings, dosage, and more. This will help reduce swelling, pain, and. Hydroxychloroquine Side Effects, Dosage, Uses, and More. Experiences taking Plaquenil for Fatigue and Muscle Pain.. Plaquenil hydroxychloroquine helps inflammation, will that.. Acupunture, yoga, massage and physical therapy might help as well. Changing your diet to eliminate gluten, increase omega 3's, eliminate processed foods might also help with fatigue and joint pains. Lastly, a drug that is related to plaquenil called quinacrine may be helpful to take. This has lower incidence of retinal toxicity than plaquenil. Treating the Pain and Fatigue. If the patient has widespread pain and fatigue in Sjogren's, there is a significant chance that they also have lupus, rheumatoid arthritis RA or fibromyalgia. The diagnosis and treatment of lupus and RA are fairly straightforward. Here are 10 things to keep in mind when using Plaquenil Take it on a regular schedule, meaning at the same time each day. Take Plaquenil EXACTLY as prescribed by your physician. Do not stop taking the medication without first speaking to your doctor. Taking Hydroxychloroquine with food and/or milk can help prevent stomach upset.