Plaquenil screening recommendations

Discussion in 'International Pharmacy' started by ed_ps, 20-Mar-2020.

  1. Remaker Well-Known Member

    Plaquenil screening recommendations


    Implementation of the guideline’s recommendations will prevent iatrogenic visual loss. The new guideline also makes recommendations regarding the techniques and timing of baseline and follow-up screening tests for both hydroxychloroquine and chloroquine retinopathy.

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    Screening guidelines were updated this year, with some pertinent changes for our profession to note. Cumulative dose is no longer a risk factor, but more of a tool in the screening of our patients. Hydroxychloroquine Plaquenil is considered a disease-modifying anti-rheumatic drug DMARD. It can decrease the pain and swelling of arthritis, prevent joint damage and reduce the risk of long- term disability. Hydroxychloroquine is in a class of medications that was first used to prevent and treat malaria. Today it is recommended that every single person on Plaquenil get a visual field 10-2 test, plus one of the three other highly sensitive screening tests the FAF fundus autofluorescence imaging, the SD-OCT spectral domain optical coherence, or the multifocal electroretinogram mfERG,” Thomas says.

    In general, hydroxychloroquine is a safe and cost-effective medication, particularly when compared to newer anti-inflammatory medicines which can more significant adverse effects on the body. Hydroxychloroquine is a medicine that is effective in treating various long-term inflammatory disorders of the joints and skin.

    Plaquenil screening recommendations

    Hydroxychloroquine Plaquenil Toxicity and Recommendations., PATIENT FACT SHEET Hydroxychloroquine Plaquenil

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  5. The most recent 2016 guidelines from the American Academy of Ophthalmology AAO recommend the dose of HCQ ≤5 mg/kg real body weight to minimize toxicity 1. According to these new guidelines, the risk of HCQ retinal toxicity is less than 1 % in the first year of therapy and less than 2 % up to 10 years of therapy.

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    The results of screening should be communicated back to the prescribing doctor, patient and GP as normal, possible or definite hydroxychloroquine retinopathy. It is the prescribing doctor’s responsibility to ensure their patients are adequately screened and to act on the results of screening. In 2011 the American Academy of Ophthalmology published new clinical guidelines for appropriate annual screenings for those patients taking Plaquenil. These guidelines are much different from the previous 2002 recommendations, and many practicing doctors were trained with the 2002 guidelines in mind. Take Plaquenil with a meal or a glass of milk. To prevent malaria Start taking Plaquenil 2 weeks before entering an area where malaria is common. Continue taking the medicine regularly during your stay and for at least 8 weeks after you leave the area. To treat malaria Plaquenil is usually given for 3 days.

     
  6. Pesh Well-Known Member

    Download PDF Many systemic medications may cause retinal toxicity. Hydroxychloroquine-Induced Retinal Toxicity - American. Hydroxychloroquine and Chloroquine Retinopathy. Eye screening for patients taking hydroxychloroquine Plaquenil
     
  7. PedroSumkin Well-Known Member

    PDF Hydroxychloroquine in systemic lupus erythematosus SLE Hydroxychloroquine HCQ is an alkalinizing lysosomatropic drug that accumulates in lysosomes where it inhibits some important functions by increasing the pH. HCQ has proved to be effective in a number of autoimmune diseases including systemic lupus erythematosus SLE.

    Hydroxychloroquine and Colchicine Induced Myopathy The.