Trametinib and hydroxychloroquine

Discussion in 'International Pharmacy' started by Markus, 26-Feb-2020.

  1. mnn New Member

    Trametinib and hydroxychloroquine


    Researchers from Huntsman Cancer Institute (HCI) at the University of Utah have now come up with a potential new therapy for pancreatic cancer patients. The researchers have found that a new combination therapeutic approach can effectively fight the disease and prolong survival among patients.

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    Huntsman Cancer Institute, University of Utah Photo National Cancer Institute Investigators at the Huntsman Cancer Institute at the University of Utah are conducting a Phase I clinical trial to study the side effects and best dose of hydroxychloroquine when given together with trametinib MEKINIST ®, Novartis in treating patients with pancreatic cancer that has spread to nearby tissue, lymph nodes, or other places in the body and cannot be removed by surgery. Compare Chloroquine vs Hydroxychloroquine head-to-head with other drugs for uses, ratings, cost, side effects, interactions and more. Chloroquine rated 10.0/10 vs Hydroxychloroquine rated 6.7/10 in overall patient satisfaction. Finally, the observed anti-tumor effects of combination trametinib plus chloroquine were observed against a NRAS mutated melanoma and a BRAF mutated colorectal patient-derived xenografts. These data may warrant testing this combination therapy in patients with KRAS mutated pancreatic cancers, a disease for which new pathway-targeted therapies.

    The results of the study were published in the latest issue of the journal The team has opened up the therapy for clinical trials at HCI as well as other centres across United States along with support from University of California, San Francisco, and Columbia University in New York. The therapy has shown promise in the laboratory set up and now is ready for use among human patients in its clinical trials.

    Trametinib and hydroxychloroquine

    Trametinib and Hydroxychloroquine in Treating Patients., Chloroquine vs Hydroxychloroquine Comparison -

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  7. Dabrafenib, Trametinib and Hydroxychloroquine in Patients With Advanced BRAF Mutant Melanoma BAMM The safety and scientific validity of this study is the responsibility of the study sponsor and investigators.

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    • PLAQUENIL HYDROXYCHLOROQUINE SULFATE TABLETS, USP DESCRIPTION.

    Jan 31, 2019 Trametinib and Hydroxychloroquine in Treating Patients With Pancreatic Cancer THREAD The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U. S. Federal Government. Apr 10, 2019 Plaquenil hydroxychloroquine belongs to a group of medicines called quinolines. Plaquenil is used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Malaria is common in areas such as Africa, South America, and Southern Asia. Hydroxychloroquine Plaquenil is a drug that is classified as an anti-malarial drug. Plaquenil is prescribed for the treatment or prevention of malaria. It is also prescribed for the treatment of rheumatoid arthritis, lupus, and the side effects of lupus such as hair loss, joint pain, and more.

     
  8. mauzer New Member

    Prescribed for Lyme Disease - Arthritis, Dermatomyositis, Malaria, Malaria Prevention, Rheumatoid Arthritis, Systemic Lupus Erythematosus. Atovaquone-proguanil versus chloroquine-proguanil for malaria. Malaria prophylaxis - Wikipedia Prophylaxis of Malaria - PubMed Central PMC
     
  9. warf XenForo Moderator

    Dr. Reddy's rolls out generic of Plaquenil - CDR – Chain. Dr. Reddy’s rolls out generic of Plaquenil July 11, 2018 HYDERABAD, India and PRINCETON, N. J. — Dr. Reddy’s Laboratories announced the launch of hydroxychloroquine sulfate tablets USP, 200 mg, a therapeutic equivalent generic version of Plaquenil hydroxychloroquine sulfate tablets, in the U. S. market, approved by the U. S. Food and Drug.

    Dr. Reddy’s announces launch of Plaquenil generic