Chloroquine is now uncommonly used in favor of its derivative hydroxychloroquine. In the United States, hydroxychloroquine is most often used for its anti-inflammatory effects in rheumatology and dermatology. Chloroquine metabolism Plaquenil dosage alopecia PlaquenilMaculopathy Anthony’DeWilde’OD’FAAO’ COPE’#34898’PS’ Event#’104151’ Expiration’6/15/15’ CourseDescription Plaquenil’maculopathy. Hydroxychloroquine Maculopathy An Update on Screening and Diagnosis A brief guide for imaging SHIRI SHULMAN, MD. H ydroxychloroquine HCQ; Plaquenil, Sanofi, Bridgewater, NJ is an antimalarial agent that is also commonly used as a treatment for a variety of rheumatologic and dermatologic conditions, such as rheumatoid arthritis and systemic lupus erythematosus. Chloroquine and hydroxychloroquine can cause toxic retinopathy due to their binding of melanin in the retinal pigmented epithelium RPE as well as direct toxicity to retinal ganglion cells. Early findings include mottling of the RPE and blunted foveal reflex. As the retinopathy progresses, a bull's-eye maculopathy develops, as seen in these. While early toxicity may be asymtomatic, patients with more advanced stage of toxicity may complain of color vision changes or paracentral scotomas. Its toxic effects on the retina are seen in the macula. Oct findings of plaquenil maculopathy Hydroxychloroquine-related retinal toxicity Rheumatology Oxford., Retinal Physician - Hydroxychloroquine Maculopathy An Update on. Hydroxychloroquine sulfate 200 mg pilWhat is the best time of day to take plaquenilPlaquenil injectionsDoxycycline plaquenil Dec 04, 2014 Hydroxychloroquine HCQ retinopathy can result in permanent vision loss. In early stages of HCQ retinopathy, patients are usually asymptomatic with preservation of visual acuity. We aspire that our review, in conjunction with the American Academy of. Hydroxychloroquine retinopathy A review of imaging. Bull's-eye maculopathy due to hydroxychloroquine toxicity. Hydroxychloroquine Plaquenil Toxicity and Recommendations.. Dence of hydroxychloroquine maculopathy. Table. Clinical, High-Speed Ultra–High-Resolution Optical Coherence Tomography, and Multifocal Electroretinogram Findings From Patients Receiving Hydroxychloroquine Patient No./ Age, y Hydroxychloroquine Dosage, mg/d Diagnosis Treatment, y Symptoms Visual Acuity, OD, OS Color Vision Visual Fields mfERG. These findings were suggestive of hydroxychloroquine retinopathy, and the patient was advised to discontinue hydroxychloroquine. At 6-month follow-up, the patient’s visual acuity remained 20/20. Plaquenil Toxicity - Bulls Eye Maculopathy 878 views 70-year-old woman with systemic Lupus erythematosus and clotting problems. She was on the Plaquenil for about eight years and then off the Plaquenil for the last eight years because she developed macular toxicity. Although her vision was hazy, it was stable.