Treatment of discoid lupus erythematosus with chloroquine

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  1. sher New Member

    Treatment of discoid lupus erythematosus with chloroquine


    Although survival rates have improved, over one half of patients with systemic lupus erythematosus have permanent damage in one or more organ systems. Arthritis and cutaneous manifestations are most common, but renal, hematologic and neurologic manifestations contribute largely to morbidity and mortality.

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    Aug 21, 2018 Hydroxychloroquine is the first-line systemic agent for discoid lupus erythematosus DLE, whereas chloroquine is considered second-line antimalarial therapy in the United States. Hydroxychloroquine Plaquenil, chloroquine Aralen, and quinacrine Atabrine are medications that were originally used to prevent or treat malaria. However, during World War II it was also found that these medications were effective in treating the symptoms of lupus. Oral thalidomide has increasingly been accepted as a treatment for cutaneous lupus erythematosus CLE, including DLE lesions, that have not responded to other treatments. Stevens RJ, Andujar C, Edwards CJ, et al. Thalidomide in the treatment of the cutaneous manifestations of lupus erythematosus experience in sixteen consecutive patients.

    Systemic lupus erythematosus has fascinated physicians for almost a century and remains the prototypic autoimmune disease. Treatment approaches emphasize using a combination of drugs to minimize chronic exposure to corticosteroids.

    Treatment of discoid lupus erythematosus with chloroquine

    Lupus Erythematosus Treated with a Combination of., Treating Lupus with Anti-Malarial Drugs Johns Hopkins Lupus.

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  6. Discoid lupus erythematosus DLE is a form of lupus that mainly affects your skin. DLE is different from systemic lupus erythematosus SLE, the most common form of lupus, which can affect any part of the body.

    • Discoid Lupus Erythematosus Only Affects Your Skin.
    • Discoid lupus erythematosus - Treatment algorithm BMJ..
    • Discoid Lupus Rash Symptoms, Treatment, and Causes.

    Hydroxychloroquine is also an antirheumatic medicine and is used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. Important information. Taking hydroxychloroquine long-term or at high doses may cause irreversible damage to the retina of your eye. Original Article from The New England Journal of Medicine — Chronic Discoid Lupus ErythematosusTreatment with Daraprim and Chloroquine Diphosphate Aralen Bjornberg A, Hellgren L. Topical treatment of chronic discoid lupus erythematosus with betamethason-17-valerate and fluocinolone acetonie-a double blind study. Indian J Dermatol 1966;. Mitchell AD, Mitchell DM. Fluocinolone acetonide in the treatment of chronic discoid lupus erythematosus.

     
  7. sevcom XenForo Moderator

    Diet, stress, poor sleep and changes in gut bacteria may all trigger symptoms. Chronic Rhinosinusitis and Irritable Bowel Syndrome A Case. Hydroxychloroquine for Crohns Disease and Ulcerative Colitis. Gastrointestinal disease in Sjogren’s syndrome related to.
     
  8. les-nick Guest

    Chloroquine has long been used in the treatment or prevention of malaria from Plasmodium vivax, P. malariae, excluding the malaria parasite Plasmodium falciparum, for it started to develop widespread resistance to it. CHLOROQUINE PHOSPHATE, USP Primaquine - Wikipedia Chloroquine - FDA prescribing information, side effects.
     
  9. artmedia XenForo Moderator

    Inflammatory Osteoarthritis And Plaquenil Plaquenil reduces inflammation in many Rheumatic disorders, the mode of action is pretty complicated though so I shan't bore you with all the details, but basically it prevents your dendritic cells these are messengers for your immune system, if you will from interacting with your T-Cells a special type of white blood cell which through a convoluted and boring process, causes inflammation.

    What Is Plaquenil? - American Academy of Ophthalmology