One class of medications can lead to more severe vision loss in people with the wet form of the disease, and another class of drugs may have a beneficial effect. Fortunately, very few prescription drugs have any known detrimental effects for people with AMD. How long will plaquenil stay in your system Aralene Plaquenil-induced maculopathy is a form of retinal toxicity that is associated with long-term use of of the anti-inflammatory medication plaquenil. The drug-induced maculopathy is associated with the following risk factors Cumulative dose level of 1,000 grams of plaquenil Patients with existing retinal or macular disease The major macular disease which we know more about is age-related macular degeneration ARMD for which the NIH has guideline to help protect the macula including oral supplements of lutein and zeaxanthin. It is not known whether this would benefit patients on HCQ or those with toxicity. Plaquenil has active ingredients of hydroxychloroquine sulfate. It is often used in systemic lupus erythematosus. Check the latest outcomes from 50,877 Plaquenil users, or browse all drugs. What is Macular degeneration? Doctors often put patients with certain potentially life-threatening cardiovascular conditions on this blood thinner. Warfarin (Coumadin®), which is an anticoagulant blood thinner, is one exception. Plaquenil use in macular degen Plaquenil Hydroxychloroquine - Side Effects, Dosage., Plaquenil - Eye Doctor MD Chloroquine and proguanil breastfeedingSide effects of plaquenil depressionEye toxicity hydroxychloroquineTumors associated with plaquenilWeiggt gain tryibg to get off plaquenil If you have any questions or want more information about any drug on this list and its possible links to macular degeneration, talk to your prescribing physician and/or ophthalmologist. You may also want to discuss whether the use of a drug on this list outweighs the increased risk of side effects compared with other treatments. Medication Cautions in Macular Degeneration - AMDF. Macular degeneration in Plaquenil how severe and when it.. Plaquenil Side Effects on Your Eyes and Vision. Focus on Eyes Long-term Plaquenil intake can affect your vision by Dr. Juan Carlos de Rivero Vaccari and Dr. Frederick Ho, Special to FLORIDA TODAY Plaquenil, or hydroxychloroquine, is an anti-malaria medication that is commonly used to treat autoimmune disorders. The risk for retinal toxicity begins once the patient has used Plaquenil for five to seven years and/or has taken a cumulative dose of more than 1,000g. Patients with renal or hepatic dysfunction are at an increased risk of toxicity. 1 Other risk factors for retinal toxicity include short stature, obesity. Anyway I was diagnosed with dry macular degeneration 7 years ago. A recent exam showed it has worsened. I have also seen 3 rheumatologists, and 2 of them say I should take Plaquenil and the risk of damage to my macula is not big enough to not take the Plaquenil.