It also associated with rheumatic disorders such as rheumatoid arthritis, and it is rheumatoid factor positive in 90 percent of cases. Reading the warnings, I see that there is concern about effects on the eyes (retinas). I am very concerned about this and am wondering if anyone out there has been put on an alternative drug to treat their SS. Can you donate blood if you are on plaquenil How long does plaquenil take to work for lupus I originally took Plaquenil Sanofi but this brand is now discontinued. The generic form of this, on my prescription, gives me serious digestion and stomach upsets to a point I spent months trying to figure out what I thought was irritable bowel syndrome. Has anyone found a good alternative UK brand that doesn't create this side affect. Hello! Here is a short list Prednisone, Imuran, Remicade, Methotrexate Later sidesteps Prednisone's side effects, which include weight gain, mood swings, diabetes and eye problems, such as cataracts. Substitutes and alternatives to Plaquenil hydroxychloroquine for uses like Rheumatoid arthritis, Lupus and Malaria Plaquenil hydroxychloroquine Alternatives & Similar Drugs - Skip to full site navigation The side effects of these medications are far scarier! I have several issues with my retinas already, and don't feel comfortable putting them at more risk. There are other medications but they're usually saved for those with a more severe disease, particularly joint problems. Alternatives to plaquenil for lupus Healthboards - Immune & Autoimmune - Lupus Alternatives to, Alternatives to plaquenil Anti-Inflammatories discussions. Hydroxychloroquine interference with warfarinSd-oct and plaquenil toxicity Substitutes and alternatives to Plaquenil hydroxychloroquine for uses like Rheumatoid arthritis, Lupus and Malaria Plaquenil hydroxychloroquine Alternatives & Similar.. Plaquenil hydroxychloroquine Alternatives & Similar Drugs.. Alternatives to Methotrexate lupus. Plaquenil is a slow-acting drug, meaning that it can take up to 6 months to experience the full benefits of this medication, but it is possible for symptoms to improve in as few as 1 or 2 months. Plaquenil and other antimalarials are the key to controlling lupus long-term, and some lupus patients may be on Plaquenil for the rest of their lives. Dec 29, 2004 i to have been taking plaquenil for at least 6 to 8 months not sure a lil lupie lol anyway and i do feel a difference in my eyes plus my liver enzymes are up i believe that the highest is 47 and mines is 48 the doc says not dangerously high but we need to keep an eye on it. im not sure but i thought that the enzymes were up cuz of the prednisone but now ill have to ask the doc. i too want. I am taking Plaquenil since 10 there are side effects,but your doctor also will check your blood on a regular basis and would detect right away if there would be something wrong with your liver or you have Lupus, it would be more dangerous for your inner organs,if you wouldn`t take any medications.