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    Prednisone is used for many different autoimmune diseases and inflammatory conditions, including: asthma, COPD, CIDP, rheumatic disorders, allergic disorders, ulcerative colitis and Crohn's disease, adrenocortical insufficiency, hypercalcemia due to cancer, thyroiditis, laryngitis, severe tuberculosis, urticaria (hives), lipid pneumonitis, pericarditis, multiple sclerosis, nephrotic syndrome, sarcoidosis, to relieve the effects of shingles, lupus, myasthenia gravis, poison oak exposure, Ménière's disease, autoimmune hepatitis, giant-cell arteritis, the Herxheimer reaction that is common during the treatment of syphilis, Duchenne muscular dystrophy, uveitis, and as part of a drug regimen to prevent rejection after organ transplant. It is important in the treatment of acute lymphoblastic leukemia, non-Hodgkin lymphomas, Hodgkin's lymphoma, multiple myeloma, and other hormone-sensitive tumors, in combination with other anticancer drugs. Prednisone can be used in the treatment of decompensated heart failure to increase renal responsiveness to diuretics, especially in heart failure patients with refractory diuretic resistance with large dose of loop diuretics. In terms of the mechanism of action for this purpose: prednisone, a glucocorticoid, can improve renal responsiveness to atrial natriuretic peptide by increasing the density of natriuretic peptide receptor type A in the renal inner medullary collecting duct, inducing a potent diuresis. Short-term side effects, as with all glucocorticoids, include high blood glucose levels (especially in patients with diabetes mellitus or on other medications that increase blood glucose, such as tacrolimus) and mineralocorticoid effects such as fluid retention. The mineralocorticoid effects of prednisone are minor, which is why it is not used in the management of adrenal insufficiency, unless a more potent mineralocorticoid is administered concomitantly. It can also cause depression or depressive symptoms and anxiety in some individuals. xenical and alli It prevents the release of substances in the body that cause inflammation. Prednisone is used as an anti-inflammatory or an immunosuppressant medication. Prednisone treats many different conditions such as allergic disorders, skin conditions, ulcerative colitis, arthritis, lupus, psoriasis, or breathing disorders. Prednisone treats many different conditions such as allergic disorders, skin conditions, ulcerative colitis, arthritis, lupus, psoriasis, or breathing disorders. You should avoid taking prednisone if you have a fungal infection that requires oral antifungals. Topical antifungals may not be an issue, but always let your doctor know what medicines you’re taking before starting Prednisone. Steroid medication can weaken your immune system, making it easier for you to get an infection. Avoid being near people who are sick or have infections.

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    Today’s live discussion is about the management and side affects of prednisone. Mazen Dimachkie with us to answer your questions about this life-saving but troublesome drug. Dimachkie is at the University of Kansas Medical Center, where he directs the Neuromuscular Section and also serves as Professor of Neurology and director of the Electromyography Laboratory and two fellowship training programs in Clinical Neurophysiology and in Neuromuscular Medicine. He is a member of TMA’s medical advisory board and will be joining us at the Annual Patient Conference in September. Many of you have submitted questions about this topic, and you are also welcome to submit questions in the course of the session. Dimachkie will pass over questions that have already been answered. Since we have limited time, please try to keep your questions of general interest. A transcript, with the names of the participants removed, will be available shortly after the live discussion. The NICE British National Formulary (BNF) and British National Formulary for Children (BNFc) sites are only available to users in the UK, Crown Dependencies and British Overseas Territories. If you believe you are seeing this page in error please contact us.

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  5. Hello @barbararene, my first episode of PMR took almost 3 years to get off prednisone. I started with the 20 mg and started tapering after a few months. The hardest for me was the last year where for about 6 months I was going back and forth between 1 mg and 1/2 mg dosage.

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